Necrotizing Enterocolitis, Infant Formula & Oligosaccharides – Doxycycline & Alzheimer’s – Coffee & Inflammation

Digested formula but not digested fresh human milk causes death of intestinal cells in vitro: implications for necrotizing enterocolitis “Necrotizing enterocolitis is a medical condition where a portion of the bowel dies. It typically occurs in newborns that are either premature or otherwise unwell. Symptoms may include poor feeding, bloating, decreased activity, blood in the […]

Progesterone – Substance Use Disorder * Biotin – Hormone Lab Results * Vitamin E – HPA-Axis

Role of Exogenous Progesterone in the Treatment of Men and Women with Substance Use Disorders: A Narrative Review Progesterone and it’s metabolite allopregnanolone show promise in substance use disorder, specifically with nicotine and cocaine. “…progesterone, attenuates the craving for and the euphoric effects of drugs of abuse. Research to date has demonstrated that progesterone may […]

* Opioids – Fertility & Hormones * B1/Thiamine – Alcohol & Dementia * Sterilized Probiotics – Obesity & Diabetes * Deep Sleep – Androgens *

Tramadol (opioid) abuse is associated with a dose‐ and time‐dependent poor sperm quality and hyperprolactinaemia in young men Tramadol is a common opioid painkiller. Previous studies have shown negative reproductive effects in male animals. This study found low testosterone, high prolactin, and poor sperm parameters associated with tramadol abuse. Prolactin was doubled in the tramadol […]

SS6 * Light – Diabetic Neuropathy * BPA – Neonatal Heart * Gelatin – Neuromuscular Metabolism * Neonicotinoids – Estrogen * Trichotillomania – Progesterone

Photobiomodulation induces antinociception, recovers structural aspects and regulates mitochondrial homeostasis in peripheral nerve of diabetic mice Red light therapy improves pain and nerve function in an animal model of Diabetic Peripheral Neuropathy. Scientists prove the usefulness of a pretty simple light therapy protocol using non-pulsed light, this is a relatively simple protocol to replicate. You can […]

Study Shorts 5 * Statins – Atherosclerosis & Heart Failure * Arsenic – Moss * EBV – Autoimmune Disease * Progesterone – TBI * Frankincense – Endotoxin

Statins stimulate atherosclerosis and heart failure: pharmacological mechanisms. This article reviews some of the mechanisms that may lead to increased risk of heart problems from statin medications. They are metabolic poisons affecting vitamin K2 and CoQ10. “In contrast to the current belief that cholesterol reduction with statins decreases atherosclerosis, we present a perspective that statins […]

Study Shorts 4 * NO – Cellular Respiration * Chamomile – NO * Taurine – MELAS * Aspirin – Thromboembolism * Skin Bacteria – Cancer *

Nitric oxide regulates mitochondrial respiration and cell functions by inhibiting cytochrome oxidase Nitric oxide inhibits cellular respiration, “one of the key ways a cell releases chemical energy to fuel cellular activity”, by competing with oxygen. This may be one of the main reasons the nitric oxide can have detrimental effects.  “Nitric oxide (NO) reversibly inhibits […]

Study Shorts 3 * IBS – Bifido * Osteoarthritis – Bifido * Iron – Huntington’s * High-Fat – Compulsive Eating * Chronic Stress – Serotonin *

Protease signaling through protease activated receptor 1 mediate nerve activation by mucosal supernatants from irritable bowel syndrome but not from ulcerative colitis patients Searching for biomarkers for irritable bowel syndrome, researchers found (supernatant) fluid from IBS patients expressed different enzymes that break down protein (protease). Elevated elastase in IBS potentates serotonin and histamine. A protease […]

Study Shorts 2 * Unsaturated Fats – Vitamin D * Caloric Restriction – Grey Matter * Environmental Enrichment – Cognitive Decline * Parathyroid Hormone – Cognitive Decline * Taurine – Learning Deficits *

Polyunsaturated fatty acids decrease the apparent affinity of vitamin D metabolites for human vitamin D-binding protein. Polyunsaturated and monounsaturated fats affect vitamin D-binding protein, which transports vitamin D around the body. Mono- and polyunsaturated fatty acids markedly decreased the affinity of both 25-OHD3 and 1,25-(OH)2D3 for DBP, whereas saturated fatty acids (stearic and arachidic acid), […]

Study Shorts 1 * Coffee Antivirals * Aspirin In Preeclampsia * Ginkgo Biloba – Neuroinflammation * Allopregnanolone – Alzheimer’s * Hypothyroidism – Hypogonadism

Caffeic acid, a coffee-related organic acid, inhibits infection by severe fever with thrombocytopenia syndrome virus in vitro Caffeic acid, an organic acid found in coffee, inhibits (SFTSV) viral replication in cell culture. “CA (caffeic acid) acted on (Severe fever with thrombocytopenia syndrome  virus) and inhibited viral infection and spread, mainly by inhibiting the binding of […]